Vernal Keratoconjunctivitis:
A Rare, Sight-Threatening,
Allergic Ocular Disease

  • VKC is a rare, severe form of allergic conjunctivitis that occurs predominantly in male children1
    • Believed to be an IgE- and T cell-mediated reaction2
  • Complications, including keratitis and shield ulcers, may be sight threatening1

Images courtesy of Professor A. Leonardi.

1. Bremond-Gignac D et al. Br J Ophthalmol. 2008; 92:1097-1102; 2. Leonardi A et al. Ophthalmol Ther. 2013;2:73-88.

  • Although its name implies a seasonal (spring) course of disease, VKC occurs year-round, particularly in the tropics1
    • 23% of patients have symptoms throughout the year; in addition, approximately 16% of seasonal cases progress to perennial after a mean of 3 years from onset2

1. Vishyanond P et al. Ped Allerg Immunol. 2014;25:314-322; 2. Bonini S, et al. Ophthalmology. 2000;107:1157-1163.